• Define the cellular and molecular actors of innate immunity.
  • Describe the mechanisms that lead to the elimination of pathogens.
  • Explain the strategies of pathogens against the innate immune system.
  • Discuss the influence of genetics and microbiota on the innate immune system.
  • Present its links with the central nervous system and adaptive immunity.

Description

Innate immunity acts as a first line of defense and can destroy invading microorganisms and trigger inflammation that helps block their attack, days before the action of adaptive immunity. While adaptive immunity was at the center of researchers' concerns in the XNUMXth century, the detection of exogenous or endogenous danger signals has recently been described, as well as the action of numerous cells. This MOOC describes the actors and the entire orchestra of innate immunity against pathogens.